Coordination and policy setting involves iCCM becoming institutionalized, or fully incorporated into national priorities, policy, and programs, with corresponding capacities to sustain it. Ministries of health have the responsibility to ensure that national health policies are enacted and health priorities are achieved. Ministries are charged with developing and overseeing the standards, norms, and regulations for program implementation, and they often determine how budgeted funds are allocated among different priorities. In addition, global health programs, such as the Global Fund to Fight AIDS, Malaria, and Tuberculosis, can influence national program directions, as can the priorities of major donor organizations operating in a country. All these factors affect the interest and readiness of a country to initiate, institutionalize, or expand iCCM. Decentralization, whereby more decision-making authority is given to regional or local levels of government, may affect the environment for iCCM.